Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- MAB2370 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB2370, RRID:AB_10550502
- Product name
- ARNT monoclonal antibody, clone H1beta234
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against partial recombinant ARNT.
- Isotype
- IgG
- Antibody clone number
- H1beta234
- Storage
- Store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.
Submitted references TLR2 controls intestinal carcinogen detoxication by CYP1A1.
Lung development in the Holtzman rat is adversely affected by gestational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
(2R)-[(4-Biphenylylsulfonyl)amino]-N-hydroxy-3-phenylpropionamide (BiPS), a matrix metalloprotease inhibitor, is a novel and potent activator of hypoxia-inducible factors.
Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1alpha and -2alpha.
Antioxidants, HIF prolyl hydroxylase inhibitors or short interfering RNAs to BNIP3 or PUMA, can prevent prodeath effects of the transcriptional activator, HIF-1alpha, in a mouse hippocampal neuronal line.
Spermidine/spermine-N1-acetyltransferase 2 is an essential component of the ubiquitin ligase complex that regulates hypoxia-inducible factor 1alpha.
Do KN, Fink LN, Jensen TE, Gautier L, Parlesak A
PloS one 2012;7(3):e32309
PloS one 2012;7(3):e32309
Lung development in the Holtzman rat is adversely affected by gestational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Kransler KM, McGarrigle BP, Swartz DD, Olson JR
Toxicological sciences : an official journal of the Society of Toxicology 2009 Feb;107(2):498-511
Toxicological sciences : an official journal of the Society of Toxicology 2009 Feb;107(2):498-511
(2R)-[(4-Biphenylylsulfonyl)amino]-N-hydroxy-3-phenylpropionamide (BiPS), a matrix metalloprotease inhibitor, is a novel and potent activator of hypoxia-inducible factors.
Lauzier MC, Robitaille GA, Chan DA, Giaccia AJ, Richard DE
Molecular pharmacology 2008 Jul;74(1):282-8
Molecular pharmacology 2008 Jul;74(1):282-8
Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1alpha and -2alpha.
Puppo M, Battaglia F, Ottaviano C, Delfino S, Ribatti D, Varesio L, Bosco MC
Molecular cancer therapeutics 2008 Jul;7(7):1974-84
Molecular cancer therapeutics 2008 Jul;7(7):1974-84
Antioxidants, HIF prolyl hydroxylase inhibitors or short interfering RNAs to BNIP3 or PUMA, can prevent prodeath effects of the transcriptional activator, HIF-1alpha, in a mouse hippocampal neuronal line.
Aminova LR, Siddiq A, Ratan RR
Antioxidants & redox signaling 2008 Dec;10(12):1989-98
Antioxidants & redox signaling 2008 Dec;10(12):1989-98
Spermidine/spermine-N1-acetyltransferase 2 is an essential component of the ubiquitin ligase complex that regulates hypoxia-inducible factor 1alpha.
Baek JH, Liu YV, McDonald KR, Wesley JB, Hubbi ME, Byun H, Semenza GL
The Journal of biological chemistry 2007 Aug 10;282(32):23572-80
The Journal of biological chemistry 2007 Aug 10;282(32):23572-80
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical staining of ARNT on human glioblastoma multi-forme using ARNT monoclonal antibody, clone H1beta234 (Cat # MAB2370).
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)