Tissue expression
Cell line expression
Protein structure

DMTN

Dematin actin binding protein
DMT, EPB49 
The protein encoded by this gene is an actin binding and bundling protein that plays a structural role in erythrocytes, by stabilizing and attaching the spectrin/actin cytoskeleton to the erythrocyte membrane in a phosphorylation-dependent manner. This protein contains a core domain in the N-terminus, and a headpiece domain in the C-terminus that binds F-actin. When purified from erythrocytes, this protein exists as a trimer composed of two 48 kDa polypeptides and a 52 kDa polypeptide. The different subunits arise from alternative splicing in the 3' coding region, where the headpiece domain is located. Disruption of this gene has been correlated with the autosomal dominant Marie Unna hereditary hypotrichosis disease, while loss of heterozygosity of this gene is thought to play a role in prostate cancer progression. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2014]
More gene data

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278 antibodies from 31 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Abnova Corporation
6 antibodies
GeneTex
1 antibody
antibodies-online
82 antibodies
Aviva Systems Biology
4 antibodies
Biorbyt
46 antibodies
Invitrogen Antibodies
9 antibodies
Affinity Biosciences
2 antibodies
Cusabio Biotech Co., Ltd
2 antibodies
OriGene
5 antibodies
St John's Laboratory
2 antibodies
Boster Biological Technology
2 antibodies
Acris Antibodies GmbH
2 antibodies
Bioworld Technology, Inc
1 antibody
Novus Biologicals
5 antibodies
Atlas Antibodies
1 antibody
NovoPro Bioscience Inc.
3 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Bethyl Laboratories
1 antibody
FineTest Biotech
1 antibody
Proteintech Group
1 antibody
Abbexa
5 antibodies
Creative Biolabs
3 antibodies
Creative Diagnostics
6 antibodies
MyBioSource
3 antibodies
United States Biological
25 antibodies
MilliporeSigma / Merck KGaA
2 antibodies
Abgent
1 antibody
Leading Biology
1 antibody
ProSci
1 antibody