Tissue expression
Cell line expression

BCR

gene product
ALL, BCR1, CML, D22S11, D22S662, PHL 
A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The unregulated tyrosine kinase activity of BCR-ABL1 contributes to the immortality of leukaemic cells. The BCR protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac and other kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2020]
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681 antibodies from 40 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
3 antibodies
Invitrogen Antibodies
29 antibodies
NovoPro Bioscience Inc.
5 antibodies
antibodies-online
245 antibodies
Novus Biologicals
26 antibodies
Abnova Corporation
9 antibodies
LifeSpan BioSciences, Inc.
76 antibodies
Affinity Biosciences
8 antibodies
Cusabio Biotech Co., Ltd
9 antibodies
GeneTex
6 antibodies
Boster Biological Technology
6 antibodies
Cell Signaling Technology, Inc
2 antibodies
St John's Laboratory
7 antibodies
Biorbyt
34 antibodies
Abgent
6 antibodies
Bethyl Laboratories
3 antibodies
Abbexa
18 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
OriGene
19 antibodies
Acris Antibodies GmbH
9 antibodies
Signalway Antibody LLC
2 antibodies
Aviva Systems Biology
5 antibodies
Arigo
1 antibody
Atlas Antibodies
1 antibody
R&D Systems
1 antibody
Bioworld Technology, Inc
3 antibodies
RabMAbs
6 antibodies
ProSci
3 antibodies
Abbkine Scientific Co.Ltd.
4 antibodies
BioLegend
4 antibodies
Creative Biolabs
16 antibodies
NSJ Bioreagents
1 antibody
Abiocode, Inc.
1 antibody
United States Biological
52 antibodies
MyBioSource
6 antibodies
Leading Biology
2 antibodies
MilliporeSigma / Merck KGaA
3 antibodies
Creative Diagnostics
2 antibodies
GenWay
2 antibodies