PAB5270

antibody from Abnova Corporation

Targeting: BCR ALL, BCR1, CML, D22S11, D22S662, PHL

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB5270

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB5270, RRID:AB_1571680

Product name

BCR polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of BCR.

Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

A direct binding site for Grb2 contributes to transformation and leukemogenesis by the Tel-Abl (ETV6-Abl) tyrosine kinase.

Million RP, Harakawa N, Roumiantsev S, Varticovski L, Van Etten RA
Molecular and cellular biology 2004 Jun;24(11):4685-95

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Tyrosine phosphorylation of Grb2 by Bcr/Abl and epidermal growth factor receptor: a novel regulatory mechanism for tyrosine kinase signaling.

Li S, Couvillon AD, Brasher BB, Van Etten RA
The EMBO journal 2001 Dec 3;20(23):6793-804

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BCR/ABL directly inhibits expression of SHIP, an SH2-containing polyinositol-5-phosphatase involved in the regulation of hematopoiesis.

Sattler M, Verma S, Byrne CH, Shrikhande G, Winkler T, Algate PA, Rohrschneider LR, Griffin JD
Molecular and cellular biology 1999 Nov;19(11):7473-80

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot analysis of extracts from A-431 cells, untreated or EGF-treated (200 ng/ml, 30 min), using BCR polyclonal antibody (Cat # PAB5270) .