Antibody data
- Antibody Data
- Antigen structure
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- Product number
- orb153748 - Provider product page
- Provider
- Biorbyt
- Product name
- BCR antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody to BCR. The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.
- Reactivity
- Human, Mouse, Rat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 50 ul
- Storage
- Store at -20°C. Avoid freeze / thaw cycles.
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