orb153748

antibody from Biorbyt
Targeting: BCR ALL, BCR1, CML, D22S11, D22S662, PHL
Provider product page for orb153748
Western blot
Immunohistochemistry

Antibody data

Product number
orb153748 - Provider product page
Provider
Biorbyt
Product name
BCR antibody
Antibody type
Polyclonal
Description
Rabbit polyclonal antibody to BCR. The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.
Reactivity
Human, Mouse, Rat
Conjugate
Unconjugated
Isotype
IgG
Vial size
50 ul
Storage
Store at -20°C. Avoid freeze / thaw cycles.
BCR protein structure - orb153748 shown in red.