SERPINB9

This gene encodes a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. This protein inhibits the activity of the effector molecule granzyme B. Overexpression of this protein may prevent cytotoxic T-lymphocytes from eliminating certain tumor cells. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Mar 2012]

Description

Serpin family B member 9

Tissue specificity

Tissue enhanced (lymphoid tissue, placenta)

Subcell location

Nucleoplasm, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

6:p25.2 (2887270 - 2903309)

Ensembl ID

ENSG00000170542  (ver. 103.38)

Orthologs

-

UniProt

P50453

neXtProt

NX_P50453

Human splice variants