SERPINB9

This gene encodes a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. This protein inhibits the activity of the effector molecule granzyme B. Overexpression of this protein may prevent cytotoxic T-lymphocytes from eliminating certain tumor cells. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Mar 2012]

Description

serpin family B member 9

Protein family

Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

6:p25.2 (2887270 - 2903309)

Ensembl ID

ENSG00000170542  (ver. 99.38)

Orthologs

-

UniProt

P50453

neXtProt

NX_P50453

Human splice variants