SERPINB9

This gene encodes a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. This protein inhibits the activity of the effector molecule granzyme B. Overexpression of this protein may prevent cytotoxic T-lymphocytes from eliminating certain tumor cells. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Mar 2012]

Description

serpin peptidase inhibitor, clade B (ovalbumin), member 9

Protein family

Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014)

Chromosome

6:p25.2 (2887266 - 2903280)

Ensembl ID

ENSG00000170542  (ver. 84.38)

Orthologs

-

UniProt

P50453

neXtProt

NX_P50453

Human splice variants