ABIN180930

antibody from antibodies-online

Targeting: SERPINB9 CAP3, PI9

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

ABIN180930

Provider

antibodies-online

Product name

anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) antibody

Antibody type

Monoclonal

Description

Affinity Chromatography on Protein G

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

7D8

Vial size

0.1 mg

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.Shelf life: one year from despatch.

References

Submitted references

SerpinB9 expression in human renal tubular epithelial cells is induced by triggering of the viral dsRNA sensors TLR3, MDA5 and RIG-I.

Heutinck KM, Kassies J, Florquin S, ten Berge IJ, Hamann J, Rowshani AT
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2012 Jul;27(7):2746-54

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The intracellular granzyme B inhibitor, proteinase inhibitor 9, is up-regulated during accessory cell maturation and effector cell degranulation, and its overexpression enhances CTL potency.

Hirst CE, Buzza MS, Bird CH, Warren HS, Cameron PU, Zhang M, Ashton-Rickardt PG, Bird PI
Journal of immunology (Baltimore, Md. : 1950) 2003 Jan 15;170(2):805-15

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The granzyme B inhibitor, PI-9, is present in endothelial and mesothelial cells, suggesting that it protects bystander cells during immune responses.

Buzza MS, Hirst CE, Bird CH, Hosking P, McKendrick J, Bird PI
Cellular immunology 2001 May 25;210(1):21-9

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Perforin-independent expression of granzyme B and proteinase inhibitor 9 in human testis and placenta suggests a role for granzyme B-mediated proteolysis in reproduction.

Hirst CE, Buzza MS, Sutton VR, Trapani JA, Loveland KL, Bird PI
Molecular human reproduction 2001 Dec;7(12):1133-42