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- Antigen structure
- References [14]
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- Immunohistochemistry [1]
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- Product number
- 25155-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#25155-1-AP, RRID:AB_2810874
- Product name
- ATG2B antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ATG2B antibody (Cat. #25155-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Lysosome damage triggers direct ATG8 conjugation and ATG2 engagement via non-canonical autophagy.
TFAM knockdown undermines SQSTM1 mRNA stability but retards autophagy flux and inhibits tumor cells proliferation under starvation conditions.
Comprehensive analysis of autophagic functions of WIPI family proteins and their implications for the pathogenesis of β-propeller associated neurodegeneration.
A phosphoinositide signalling pathway mediates rapid lysosomal repair.
SHISA5/SCOTIN restrains spontaneous autophagy induction by blocking contact between the ERES and phagophores.
Loss of Atg2b and Gskip Impairs the Maintenance of the Hematopoietic Stem Cell Pool Size.
LncRNA MEG3 promotes the sensitivity of bortezomib by inhibiting autophagy in multiple myeloma.
The autophagy protein ATG9A enables lipid mobilization from lipid droplets.
ATG9A protects the plasma membrane from programmed and incidental permeabilization.
The c-Myc/miR-27b-3p/ATG10 regulatory axis regulates chemoresistance in colorectal cancer.
A conserved ATG2-GABARAP family interaction is critical for phagophore formation.
Fine particulate matter inhibits phagocytosis of macrophages by disturbing autophagy.
TOM40 Targets Atg2 to Mitochondria-Associated ER Membranes for Phagophore Expansion.
Architecture of the ATG2B-WDR45 complex and an aromatic Y/HF motif crucial for complex formation.
Cross J, Durgan J, McEwan DG, Tayler M, Ryan KM, Florey O
The Journal of cell biology 2023 Dec 4;222(12)
The Journal of cell biology 2023 Dec 4;222(12)
TFAM knockdown undermines SQSTM1 mRNA stability but retards autophagy flux and inhibits tumor cells proliferation under starvation conditions.
Jiang X, Xu Y, Yang J, Wang J, Gao L, Yu L
Cell biology international 2023 Aug;47(8):1453-1465
Cell biology international 2023 Aug;47(8):1453-1465
Comprehensive analysis of autophagic functions of WIPI family proteins and their implications for the pathogenesis of β-propeller associated neurodegeneration.
Shimizu T, Tamura N, Nishimura T, Saito C, Yamamoto H, Mizushima N
Human molecular genetics 2023 Aug 7;32(16):2623-2637
Human molecular genetics 2023 Aug 7;32(16):2623-2637
A phosphoinositide signalling pathway mediates rapid lysosomal repair.
Tan JX, Finkel T
Nature 2022 Sep;609(7928):815-821
Nature 2022 Sep;609(7928):815-821
SHISA5/SCOTIN restrains spontaneous autophagy induction by blocking contact between the ERES and phagophores.
Lee JE, Kim N, Jung M, Mun JY, Yoo JY
Autophagy 2022 Jul;18(7):1613-1628
Autophagy 2022 Jul;18(7):1613-1628
Loss of Atg2b and Gskip Impairs the Maintenance of the Hematopoietic Stem Cell Pool Size.
Sakai SS, Hasegawa A, Ishimura R, Tamura N, Kageyama S, Komatsu-Hirota S, Abe M, Ling Y, Okuda S, Funayama M, Kikkawa M, Miura Y, Sakimura K, Narita I, Waguri S, Shimizu R, Komatsu M
Molecular and cellular biology 2022 Jan 20;42(1):e0002421
Molecular and cellular biology 2022 Jan 20;42(1):e0002421
LncRNA MEG3 promotes the sensitivity of bortezomib by inhibiting autophagy in multiple myeloma.
Zang X, Wang J, Xia Y, Li J, Chen L, Gu Y, Shen X
Leukemia research 2022 Dec;123:106967
Leukemia research 2022 Dec;123:106967
The autophagy protein ATG9A enables lipid mobilization from lipid droplets.
Mailler E, Guardia CM, Bai X, Jarnik M, Williamson CD, Li Y, Maio N, Golden A, Bonifacino JS
Nature communications 2021 Nov 19;12(1):6750
Nature communications 2021 Nov 19;12(1):6750
ATG9A protects the plasma membrane from programmed and incidental permeabilization.
Claude-Taupin A, Jia J, Bhujabal Z, Garfa-Traoré M, Kumar S, da Silva GPD, Javed R, Gu Y, Allers L, Peters R, Wang F, da Costa LJ, Pallikkuth S, Lidke KA, Mauthe M, Verlhac P, Uchiyama Y, Salemi M, Phinney B, Tooze SA, Mari MC, Johansen T, Reggiori F, Deretic V
Nature cell biology 2021 Aug;23(8):846-858
Nature cell biology 2021 Aug;23(8):846-858
The c-Myc/miR-27b-3p/ATG10 regulatory axis regulates chemoresistance in colorectal cancer.
Sun W, Li J, Zhou L, Han J, Liu R, Zhang H, Ning T, Gao Z, Liu B, Chen X, Ba Y
Theranostics 2020;10(5):1981-1996
Theranostics 2020;10(5):1981-1996
A conserved ATG2-GABARAP family interaction is critical for phagophore formation.
Bozic M, van den Bekerom L, Milne BA, Goodman N, Roberston L, Prescott AR, Macartney TJ, Dawe N, McEwan DG
EMBO reports 2020 Mar 4;21(3):e48412
EMBO reports 2020 Mar 4;21(3):e48412
Fine particulate matter inhibits phagocytosis of macrophages by disturbing autophagy.
Li Y, Yong YL, Yang M, Wang W, Qu X, Dang X, Shang D, Shao Y, Liu J, Chang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16716-16735
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16716-16735
TOM40 Targets Atg2 to Mitochondria-Associated ER Membranes for Phagophore Expansion.
Tang Z, Takahashi Y, He H, Hattori T, Chen C, Liang X, Chen H, Young MM, Wang HG
Cell reports 2019 Aug 13;28(7):1744-1757.e5
Cell reports 2019 Aug 13;28(7):1744-1757.e5
Architecture of the ATG2B-WDR45 complex and an aromatic Y/HF motif crucial for complex formation.
Zheng JX, Li Y, Ding YH, Liu JJ, Zhang MJ, Dong MQ, Wang HW, Yu L
Autophagy 2017;13(11):1870-1883
Autophagy 2017;13(11):1870-1883
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ATG2B antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ATG2B. This antibody recognizes human antigen. The ATG2B antibody has been validated for the following applications: ELISA, WB, IHC analysis.
