ABIN493153

antibody from antibodies-online

Targeting: CHRNA7

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN493153

Provider

antibodies-online

Product name

anti-Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) (Exon 5), (Variant alpha) antibody

Antibody type

Polyclonal

Antigen

Synthetic peptides corresponding to exon 5 of alfa7-2 nAChRs

Description

Affinity chromatography

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

Exon 5,Variant alpha

Vial size

0.1 mg

Concentration

0.75 - 0.95 mg/mL

Storage

Store (in aliquots) at -20°C.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

The alpha7 nicotinic acetylcholine receptor subunit exists in two isoforms that contribute to functional ligand-gated ion channels.

Severance EG, Zhang H, Cruz Y, Pakhlevaniants S, Hadley SH, Amin J, Wecker L, Reed C, Cuevas J
Molecular pharmacology 2004 Sep;66(3):420-9

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beta -Amyloid peptide activates alpha 7 nicotinic acetylcholine receptors expressed in Xenopus oocytes.

Dineley KT, Bell KA, Bui D, Sweatt JD
The Journal of biological chemistry 2002 Jul 12;277(28):25056-61

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Rat nicotinic ACh receptor alpha7 and beta2 subunits co-assemble to form functional heteromeric nicotinic receptor channels.

Khiroug SS, Harkness PC, Lamb PW, Sudweeks SN, Khiroug L, Millar NS, Yakel JL
The Journal of physiology 2002 Apr 15;540(Pt 2):425-34