Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS60756 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- ITGA8 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human ITGA8.
- Description
- Integrins are heterodimers composed of noncovalently associated transmembrane ? and ¡Â subunits. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. Integrin ?8 is expressed in contractile interstitial cells and smooth muscle cells and is upregulated in lung injury. Integrin ?8 is also a marker for smooth muscle cells, expressed as early as alpha smooth muscle actin. The Integrin ?8 chain is expressed in the glomerulus exclusively by mesangial cells and may play an important role for maintaining tissue integrity in the glomerulus during glomerular injury.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of ITGA8 pAb at 1:500 dilutionLane1:Hela whole cell lysateLane2:Raw264.7 whole cell lysate Lane3:PC12 whole cell lysate