ITGA8

gene product
Integrins are heterodimeric transmembrane receptor proteins that mediate numerous cellular processes including cell adhesion, cytoskeletal rearrangement, and activation of cell signaling pathways. Integrins are composed of alpha and beta subunits. This gene encodes the alpha 8 subunit of the heterodimeric integrin alpha8beta1 protein. The encoded protein is a single-pass type 1 membrane protein that contains multiple FG-GAP repeats. This repeat is predicted to fold into a beta propeller structure. This gene regulates the recruitment of mesenchymal cells into epithelial structures, mediates cell-cell interactions, and regulates neurite outgrowth of sensory and motor neurons. The integrin alpha8beta1 protein thus plays an important role in wound-healing and organogenesis. Mutations in this gene have been associated with renal hypodysplasia/aplasia-1 (RHDA1) and with several animal models of chronic kidney disease. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2014]
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190 antibodies from 25 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
15 antibodies
R&D Systems
12 antibodies
antibodies-online
64 antibodies
Invitrogen Antibodies
6 antibodies
NovoPro Bioscience Inc.
1 antibody
Aviva Systems Biology
2 antibodies
Biorbyt
2 antibodies
OriGene
2 antibodies
Abnova Corporation
5 antibodies
Abgent
1 antibody
Acris Antibodies GmbH
1 antibody
LifeSpan BioSciences, Inc.
47 antibodies
Affinity Biosciences
1 antibody
Atlas Antibodies
1 antibody
Bioworld Technology, Inc
1 antibody
GeneTex
1 antibody
ProSci
1 antibody
MyBioSource
2 antibodies
Boster Biological Technology
1 antibody
St John's Laboratory
1 antibody
United States Biological
17 antibodies
Creative Diagnostics
2 antibodies
Sigma-Aldrich
2 antibodies
Creative Biolabs
1 antibody
EMD Millipore
1 antibody