Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 19700-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19700-1-AP, RRID:AB_10640428
- Product name
- LRP2-Specific antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated LRP2-Specific antibody (Cat. #19700-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Dent disease 1-linked novel CLCN5 mutations result in aberrant location and reduced ion currents.
TMBIM6 promotes diabetic tubular epithelial cell survival and albumin endocytosis by inhibiting the endoplasmic reticulum stress sensor, IRE1α.
Effects of elevation of ANP and its deficiency on cardiorenal function.
Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance.
Autophagy gene ATG7 regulates albumin transcytosis in renal tubule epithelial cells.
Generation of a homozygous LRP2 knockout human embryonic stem cell line (FDCHDPe010-A-56) by CRISPR/Cas9 system.
Kidney targeted delivery of asiatic acid using a FITC labeled renal tubular-targeting peptide modified PLGA-PEG system.
Sodium-glucose cotransporter 2 inhibition attenuates protein overload in renal proximal tubule via suppression of megalin O-GlcNacylation in progressive diabetic nephropathy.
Evidence for a regulated Ca(2+) entry in proximal tubular cells and its implication in calcium stone formation.
Reduced proximal tubular expression of protein endocytic receptors in proteinuria is associated with urinary receptor shedding.
Gelofusine Attenuates Tubulointerstitial Injury Induced by cRGD-Conjugated siRNA by Regulating the TLR3 Signaling Pathway.
TGF-β inhibits alveolar protein transport by promoting shedding, regulated intramembrane proteolysis, and transcriptional downregulation of megalin.
Mouse early extra-embryonic lineages activate compensatory endocytosis in response to poor maternal nutrition.
Wang Y, Xu L, Zhang Y, Fu H, Gao L, Guan Y, Gu W, Sun J, Chen X, Yang F, Lai E, Wang J, Jin Y, Kou Z, Qiu X, Mao J, Hu L
International journal of biological macromolecules 2024 Feb;257(Pt 2):128564
International journal of biological macromolecules 2024 Feb;257(Pt 2):128564
TMBIM6 promotes diabetic tubular epithelial cell survival and albumin endocytosis by inhibiting the endoplasmic reticulum stress sensor, IRE1α.
Xie H, Shi Y, Zhou Y, Liu H
Molecular biology reports 2022 Oct;49(10):9181-9194
Molecular biology reports 2022 Oct;49(10):9181-9194
Effects of elevation of ANP and its deficiency on cardiorenal function.
Ilatovskaya DV, Levchenko V, Winsor K, Blass GR, Spires DR, Sarsenova E, Polina I, Zietara A, Paterson M, Kriegel AJ, Staruschenko A
JCI insight 2022 May 9;7(9)
JCI insight 2022 May 9;7(9)
Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance.
Chen Y, Wu X, Zhang J, Pan G, Wang X, Guo X, Wang J, Cui X, Gao H, Cheng M, Yang J, Zhang C, Jiang F
EMBO reports 2022 Feb 3;23(3):e53373
EMBO reports 2022 Feb 3;23(3):e53373
Autophagy gene ATG7 regulates albumin transcytosis in renal tubule epithelial cells.
Uchida Y, Torisu K, Ueki K, Tsuruya K, Nakano T, Kitazono T
American journal of physiology. Renal physiology 2021 Nov 1;321(5):F572-F586
American journal of physiology. Renal physiology 2021 Nov 1;321(5):F572-F586
Generation of a homozygous LRP2 knockout human embryonic stem cell line (FDCHDPe010-A-56) by CRISPR/Cas9 system.
You J, Cheng Y, Yang XJ, Chen L
Stem cell research 2021 May;53:102342
Stem cell research 2021 May;53:102342
Kidney targeted delivery of asiatic acid using a FITC labeled renal tubular-targeting peptide modified PLGA-PEG system.
He J, Chen H, Zhou W, Chen M, Yao Y, Zhang Z, Tan N
International journal of pharmaceutics 2020 Jun 30;584:119455
International journal of pharmaceutics 2020 Jun 30;584:119455
Sodium-glucose cotransporter 2 inhibition attenuates protein overload in renal proximal tubule via suppression of megalin O-GlcNacylation in progressive diabetic nephropathy.
Otomo H, Nara M, Kato S, Shimizu T, Suganuma Y, Sato T, Morii T, Yamada Y, Fujita H
Metabolism: clinical and experimental 2020 Dec;113:154405
Metabolism: clinical and experimental 2020 Dec;113:154405
Evidence for a regulated Ca(2+) entry in proximal tubular cells and its implication in calcium stone formation.
Ibeh CL, Yiu AJ, Kanaras YL, Paal E, Birnbaumer L, Jose PA, Bandyopadhyay BC
Journal of cell science 2019 Apr 30;132(9)
Journal of cell science 2019 Apr 30;132(9)
Reduced proximal tubular expression of protein endocytic receptors in proteinuria is associated with urinary receptor shedding.
Fatah H, Benfaed N, Chana RS, Chunara MH, Barratt J, Baines RJ, Brunskill NJ
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2018 Jun 1;33(6):934-943
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2018 Jun 1;33(6):934-943
Gelofusine Attenuates Tubulointerstitial Injury Induced by cRGD-Conjugated siRNA by Regulating the TLR3 Signaling Pathway.
Cen B, Liao W, Wang Z, Gao L, Wei Y, Huang W, He S, Wang W, Liu X, Pan X, Ji A
Molecular therapy. Nucleic acids 2018 Jun 1;11:300-311
Molecular therapy. Nucleic acids 2018 Jun 1;11:300-311
TGF-β inhibits alveolar protein transport by promoting shedding, regulated intramembrane proteolysis, and transcriptional downregulation of megalin.
Mazzocchi LC, Vohwinkel CU, Mayer K, Herold S, Morty RE, Seeger W, Vadász I
American journal of physiology. Lung cellular and molecular physiology 2017 Nov 1;313(5):L807-L824
American journal of physiology. Lung cellular and molecular physiology 2017 Nov 1;313(5):L807-L824
Mouse early extra-embryonic lineages activate compensatory endocytosis in response to poor maternal nutrition.
Sun C, Velazquez MA, Marfy-Smith S, Sheth B, Cox A, Johnston DA, Smyth N, Fleming TP
Development (Cambridge, England) 2014 Mar;141(5):1140-50
Development (Cambridge, England) 2014 Mar;141(5):1140-50
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The LRP2-Specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human LRP2-Specific. This antibody recognizes human antigen. The LRP2-Specific antibody has been validated for the following applications: ELISA, WB analysis.