Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Immunohistochemistry [2]
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Validation data
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- Product number
- NB110-96417 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB110-96417, RRID:AB_1260798
- Product name
- Mouse Monoclonal LRP2 Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity.
IL-6/Smad2 signaling mediates acute kidney injury and regeneration in a murine model of neonatal hyperoxia.
Cadmium Complexed with β2-Microglubulin, Albumin and Lipocalin-2 rather than Metallothionein Cause Megalin:Cubilin Dependent Toxicity of the Renal Proximal Tubule.
Autophagy Deficiency in Renal Proximal Tubular Cells Leads to an Increase in Cellular Injury and Apoptosis under Normal Fed Conditions.
Effects of ATRAP in Renal Proximal Tubules on Angiotensin-Dependent Hypertension.
Combined Structural and Functional Imaging of the Kidney Reveals Major Axial Differences in Proximal Tubule Endocytosis.
A Simple Bioreactor-Based Method to Generate Kidney Organoids from Pluripotent Stem Cells.
Human extravillous trophoblasts bind but do not internalize antiphospholipid antibodies.
Aberrant differentiation of Tsc2-deficient teratomas associated with activation of the mTORC1-TFE3 pathway.
Deletion of the angiotensin II type 1 receptor-associated protein enhances renal sodium reabsorption and exacerbates angiotensin II-mediated hypertension.
Upregulation of prolactin receptor in proximal tubular cells was induced in cardiac dysfunction model mice.
Antigen-presenting cells in parotid glands contain cystatin D originating from acinar cells.
Albumin-induced apoptosis of glomerular parietal epithelial cells is modulated by extracellular signal-regulated kinase 1/2.
Seo JA, Kang MC, Yang WM, Hwang WM, Kim SS, Hong SH, Heo JI, Vijyakumar A, Pereira de Moura L, Uner A, Huang H, Lee SH, Lima IS, Park KS, Kim MS, Dagon Y, Willnow TE, Aroda V, Ciaraldi TP, Henry RR, Kim YB
Nature communications 2020 Apr 24;11(1):2024
Nature communications 2020 Apr 24;11(1):2024
IL-6/Smad2 signaling mediates acute kidney injury and regeneration in a murine model of neonatal hyperoxia.
Mohr J, Voggel J, Vohlen C, Dinger K, Dafinger C, Fink G, Göbel H, Liebau MC, Dötsch J, Alejandre Alcazar MA
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 May;33(5):5887-5902
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 May;33(5):5887-5902
Cadmium Complexed with β2-Microglubulin, Albumin and Lipocalin-2 rather than Metallothionein Cause Megalin:Cubilin Dependent Toxicity of the Renal Proximal Tubule.
Fels J, Scharner B, Zarbock R, Zavala Guevara IP, Lee WK, Barbier OC, Thévenod F
International journal of molecular sciences 2019 May 14;20(10)
International journal of molecular sciences 2019 May 14;20(10)
Autophagy Deficiency in Renal Proximal Tubular Cells Leads to an Increase in Cellular Injury and Apoptosis under Normal Fed Conditions.
Suzuki C, Tanida I, Oliva Trejo JA, Kakuta S, Uchiyama Y
International journal of molecular sciences 2019 Dec 25;21(1)
International journal of molecular sciences 2019 Dec 25;21(1)
Effects of ATRAP in Renal Proximal Tubules on Angiotensin-Dependent Hypertension.
Kinguchi S, Wakui H, Azushima K, Haruhara K, Koguchi T, Ohki K, Uneda K, Matsuda M, Haku S, Yamaji T, Yamada T, Kobayashi R, Minegishi S, Ishigami T, Yamashita A, Fujikawa T, Tamura K
Journal of the American Heart Association 2019 Apr 16;8(8):e012395
Journal of the American Heart Association 2019 Apr 16;8(8):e012395
Combined Structural and Functional Imaging of the Kidney Reveals Major Axial Differences in Proximal Tubule Endocytosis.
Schuh CD, Polesel M, Platonova E, Haenni D, Gassama A, Tokonami N, Ghazi S, Bugarski M, Devuyst O, Ziegler U, Hall AM
Journal of the American Society of Nephrology : JASN 2018 Nov;29(11):2696-2712
Journal of the American Society of Nephrology : JASN 2018 Nov;29(11):2696-2712
A Simple Bioreactor-Based Method to Generate Kidney Organoids from Pluripotent Stem Cells.
Przepiorski A, Sander V, Tran T, Hollywood JA, Sorrenson B, Shih JH, Wolvetang EJ, McMahon AP, Holm TM, Davidson AJ
Stem cell reports 2018 Aug 14;11(2):470-484
Stem cell reports 2018 Aug 14;11(2):470-484
Human extravillous trophoblasts bind but do not internalize antiphospholipid antibodies.
Viall CA, Chen Q, Stone PR, Chamley LW
Placenta 2016 Jun;42:9-16
Placenta 2016 Jun;42:9-16
Aberrant differentiation of Tsc2-deficient teratomas associated with activation of the mTORC1-TFE3 pathway.
Kawano H, Ito Y, Kanai F, Nakamura E, Tada N, Takai S, Horie S, Kobayashi T, Hino O
Oncology reports 2015 Nov;34(5):2251-8
Oncology reports 2015 Nov;34(5):2251-8
Deletion of the angiotensin II type 1 receptor-associated protein enhances renal sodium reabsorption and exacerbates angiotensin II-mediated hypertension.
Ohsawa M, Tamura K, Wakui H, Maeda A, Dejima T, Kanaoka T, Azushima K, Uneda K, Tsurumi-Ikeya Y, Kobayashi R, Matsuda M, Uchida S, Toya Y, Kobori H, Nishiyama A, Yamashita A, Ishikawa Y, Umemura S
Kidney international 2014 Sep;86(3):570-81
Kidney international 2014 Sep;86(3):570-81
Upregulation of prolactin receptor in proximal tubular cells was induced in cardiac dysfunction model mice.
Tsuchida Y, Kaneko Y, Otsuka T, Goto K, Saito A, Yamamoto K, Yamamoto T, Narita I
Clinical and experimental nephrology 2014 Feb;18(1):65-74
Clinical and experimental nephrology 2014 Feb;18(1):65-74
Antigen-presenting cells in parotid glands contain cystatin D originating from acinar cells.
Nashida T, Sato R, Haga-Tsujimura M, Yoshie S, Yoshimura K, Imai A, Shimomura H
Archives of biochemistry and biophysics 2013 Feb 1;530(1):32-9
Archives of biochemistry and biophysics 2013 Feb 1;530(1):32-9
Albumin-induced apoptosis of glomerular parietal epithelial cells is modulated by extracellular signal-regulated kinase 1/2.
Chang AM, Ohse T, Krofft RD, Wu JS, Eddy AA, Pippin JW, Shankland SJ
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2012 Apr;27(4):1330-43
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2012 Apr;27(4):1330-43
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: LRP2 Antibody (CD7D5) [NB110-96417] - Staining on human kidney at 1:100, overnight incubation at 4C. Image from a review by a confirmed customer.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: LRP2 Antibody (CD7D5) [NB110-96417] - Staining (paraffin-embedded tissue-sections fixed in formalin) of Megalin in the brush border of the proximal tubule.