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- References [7]
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- Product number
- 24827-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- GLDC antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GLDC antibody (Cat. #24827-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Glycine decarboxylase advances IgA nephropathy by boosting mesangial cell proliferation through the pyrimidine pathway.
GLDC interacts with VPS34 to inhibit tumorigenesis and epithelial-mesenchymal transition in hepatocellular carcinoma.
Differential Inhibition of Anaplerotic Pyruvate Carboxylation and Glutaminolysis-Fueled Anabolism Underlies Distinct Toxicity of Selenium Agents in Human Lung Cancer.
Aberrant methylmalonylation underlies methylmalonic acidemia and is attenuated by an engineered sirtuin.
Blocking glycine utilization inhibits multiple myeloma progression by disrupting glutathione balance.
De novo synthesis of serine and glycine fuels purine nucleotide biosynthesis in human lung cancer tissues.
Glycine cleavage system determines the fate of pluripotent stem cells via the regulation of senescence and epigenetic modifications.
Xiong Y, Zeng F, Luo K, Wang L, Li M, Chen Y, Huang T, Xu C, Xu G, Zou H
EMBO molecular medicine 2025 Nov;17(11):3039-3063
EMBO molecular medicine 2025 Nov;17(11):3039-3063
GLDC interacts with VPS34 to inhibit tumorigenesis and epithelial-mesenchymal transition in hepatocellular carcinoma.
Song Z, Dong H, Zhang K, Qiao B, Li L, Zhang Z, Fan Z, Li J, Li Y, Liu M, Liu Y, Gu X, Zhang T
Pharmaceutical science advances 2025 Dec;3:100072
Pharmaceutical science advances 2025 Dec;3:100072
Differential Inhibition of Anaplerotic Pyruvate Carboxylation and Glutaminolysis-Fueled Anabolism Underlies Distinct Toxicity of Selenium Agents in Human Lung Cancer.
Fan TW, Winnike J, Al-Attar A, Belshoff AC, Lorkiewicz PK, Tan JL, Wu M, Higashi RM, Lane AN
Metabolites 2023 Jun 21;13(7)
Metabolites 2023 Jun 21;13(7)
Aberrant methylmalonylation underlies methylmalonic acidemia and is attenuated by an engineered sirtuin.
Head PE, Myung S, Chen Y, Schneller JL, Wang C, Duncan N, Hoffman P, Chang D, Gebremariam A, Gucek M, Manoli I, Venditti CP
Science translational medicine 2022 May 25;14(646):eabn4772
Science translational medicine 2022 May 25;14(646):eabn4772
Blocking glycine utilization inhibits multiple myeloma progression by disrupting glutathione balance.
Xia J, Zhang J, Wu X, Du W, Zhu Y, Liu X, Liu Z, Meng B, Guo J, Yang Q, Wang Y, Wang Q, Feng X, Xie G, Shen Y, He Y, Xiang J, Wu M, An G, Qiu L, Jia W, Zhou W
Nature communications 2022 Jul 11;13(1):4007
Nature communications 2022 Jul 11;13(1):4007
De novo synthesis of serine and glycine fuels purine nucleotide biosynthesis in human lung cancer tissues.
Fan TWM, Bruntz RC, Yang Y, Song H, Chernyavskaya Y, Deng P, Zhang Y, Shah PP, Beverly LJ, Qi Z, Mahan AL, Higashi RM, Dang CV, Lane AN
The Journal of biological chemistry 2019 Sep 6;294(36):13464-13477
The Journal of biological chemistry 2019 Sep 6;294(36):13464-13477
Glycine cleavage system determines the fate of pluripotent stem cells via the regulation of senescence and epigenetic modifications.
Tian S, Feng J, Cao Y, Shen S, Cai Y, Yang D, Yan R, Wang L, Zhang H, Zhong X, Gao P
Life science alliance 2019 Oct;2(5)
Life science alliance 2019 Oct;2(5)
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GLDC antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human GLDC. This antibody recognizes human, mouse antigen. The GLDC antibody has been validated for the following applications: ELISA, WB analysis.
