NDUFV3

The protein encoded by this gene is one of at least forty-one subunits that make up the NADH-ubiquinone oxidoreductase complex. This complex is part of the mitochondrial respiratory chain and serves to catalyze the rotenone-sensitive oxidation of NADH and the reduction of ubiquinone. The encoded protein is one of three proteins found in the flavoprotein fraction of the complex. The specific function of the encoded protein is unknown. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Description

NADH:ubiquinone oxidoreductase subunit V3

Tissue specificity

Tissue enhanced (skeletal muscle)

Subcell location

Mitochondria

Predicted location

Intracellular

Protein family

FDA approved drug targets
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

21 (42879644 - 42913304)

Ensembl ID

ENSG00000160194  (ver. 103.38)

Orthologs

Mouse Ndufv3: ENSMUSG00000024038

UniProt

P56181

neXtProt

NX_P56181

Human splice variants
Mouse splice variants

Protein structure