MAB4421

antibody from Abnova Corporation

Targeting: CD38

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

MAB4421

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#MAB4421, RRID:AB_10630041

Product name

CD38 monoclonal antibody, clone HIT2 (PE)

Antibody type

Monoclonal

Antigen

Native purified CD38 from human thymocytes in foetus.

Description

Mouse monoclonal antibody raised against native CD38.

Reactivity

Human

Host

Mouse

Conjugate

Yellow dye

Isotype

IgG

Vial size

100 Reactions

Storage

Store in the dark at 4°C. Do not freeze.Avoid prolonged exposure to light.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Chemotaxis of mouse bone marrow neutrophils and dendritic cells is controlled by adp-ribose, the major product generated by the CD38 enzyme reaction.

Partida-Sanchez S, Gasser A, Fliegert R, Siebrands CC, Dammermann W, Shi G, Mousseau BJ, Sumoza-Toledo A, Bhagat H, Walseth TF, Guse AH, Lund FE
Journal of immunology (Baltimore, Md. : 1950) 2007 Dec 1;179(11):7827-39

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CD38 induces apoptosis of a murine pro-B leukemic cell line by a tyrosine kinase-dependent but ADP-ribosyl cyclase- and NAD glycohydrolase-independent mechanism.

Lund FE, Muller-Steffner H, Romero-Ramirez H, Moreno-García ME, Partida-Sánchez S, Makris M, Oppenheimer NJ, Santos-Argumedo L, Schuber F
International immunology 2006 Jul;18(7):1029-42

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Kinetic competence of the cADP-ribose-CD38 complex as an intermediate in the CD38/NAD+ glycohydrolase-catalysed reactions: implication for CD38 signalling.

Cakir-Kiefer C, Muller-Steffner H, Oppenheimer N, Schuber F
The Biochemical journal 2001 Sep 1;358(Pt 2):399-406