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- Antigen structure
- References [2]
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- Product number
- ABIN1673555 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-ADAM Metallopeptidase with thrombospondin Type 1 Motif, 5 (ADAMTS5) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to a sequence at the C-terminal of human ADAMTS5, different from the related mouse and rat sequence by one amino acid.Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 100 μg
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis.
Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis.
Echtermeyer F, Bertrand J, Dreier R, Meinecke I, Neugebauer K, Fuerst M, Lee YJ, Song YW, Herzog C, Theilmeier G, Pap T
Nature medicine 2009 Sep;15(9):1072-6
Nature medicine 2009 Sep;15(9):1072-6
Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis.
Glasson SS, Askew R, Sheppard B, Carito B, Blanchet T, Ma HL, Flannery CR, Peluso D, Kanki K, Yang Z, Majumdar MK, Morris EA
Nature 2005 Mar 31;434(7033):644-8
Nature 2005 Mar 31;434(7033):644-8
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