ADAMTS5

gene product
ADAMTS11, ADMP-2
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. [provided by RefSeq, Feb 2016]
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Invitrogen Antibodies
5 antibodies
GeneTex
4 antibodies
Novus Biologicals
9 antibodies
antibodies-online
126 antibodies
Biorbyt
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LifeSpan BioSciences, Inc.
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OriGene
10 antibodies
NSJ Bioreagents
1 antibody
R&D Systems
2 antibodies
NovoPro Bioscience Inc.
5 antibodies
Boster Biological Technology
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Aviva Systems Biology
4 antibodies
Abnova Corporation
6 antibodies
Acris Antibodies GmbH
8 antibodies
MyBioSource
8 antibodies
Atlas Antibodies
3 antibodies
Creative Biolabs
66 antibodies
Abgent
5 antibodies
RabMAbs
1 antibody
St John's Laboratory
2 antibodies
United States Biological
32 antibodies
Creative Diagnostics
4 antibodies
Sigma-Aldrich
3 antibodies
Abbiotec
1 antibody
RayBiotech, Inc.
6 antibodies
Leading Biology
4 antibodies
GenWay
3 antibodies
ProSci
3 antibodies
EMD Millipore
2 antibodies
Enzo Life Sciences
1 antibody