Tissue expression
Cell line expression
Protein structure
HPRT1
Hypoxanthine phosphoribosyltransferase 1HGPRT, HPRT
The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout. [provided by RefSeq, Jun 2009]
Top validated antibodies |
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| Proteintech Group | 30 references | Polyclonal |
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| Invitrogen Antibodies | Polyclonal |
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| LSBio | Polyclonal |
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| NovoPro Bioscience Inc. | Polyclonal |
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| FineTest Biotech | Polyclonal |
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