OXTR

The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. [provided by RefSeq, Jul 2008]

Description

Oxytocin receptor

Tissue specificity

Group enriched (brain, breast)

Predicted location

Intracellular, Membrane

Protein family

FDA approved drug targets
G-protein coupled receptors
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Transporters

Chromosome

3:p25.3 (8750381 - 8769628)

Ensembl ID

ENSG00000180914  (ver. 103.38)

Orthologs

Mouse Oxtr: ENSMUSG00000049112

UniProt

P30559

neXtProt

NX_P30559

Human splice variants
Mouse splice variants