Tissue expression
Cell line expression
Protein structure
CAPN3
Calpain 3CANP3, LGMD2, LGMD2A, nCL-1, p94
Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
| antibodies-online | 4 references | Polyclonal |
|
||
| LSBio | Polyclonal |
|
|||
| Invitrogen Antibodies | Polyclonal |
|
|||
| Proteintech Group | 1 references | Polyclonal |
|
||
| OriGene | Polyclonal |
|
|||