DDX24

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which shows little similarity to any of the other known human DEAD box proteins, but shows a high similarity to mouse Ddx24 at the amino acid level. [provided by RefSeq, Jul 2008]

Description

DEAD-box helicase 24

Tissue specificity

Low tissue specificity

Subcell location

Nucleoli, Cytosol

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

14 (94048287 - 94081212)

Ensembl ID

ENSG00000089737  (ver. 103.38)

Orthologs

Mouse Ddx24: ENSMUSG00000041645

UniProt

Q9GZR7

neXtProt

NX_Q9GZR7

Human splice variants
Mouse splice variants

Protein structure