Tissue expression
Cell line expression
Protein structure
NCOR2
Nuclear receptor corepressor 2CTG26, SMRT, SMRTE, TNRC14, TRAC-1
This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2011]
Top validated antibodies |
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GeneTex | GTX70246 | 2 references | Monoclonal |
WB
ICC
IP
IHC
ChIP
|
|
Invitrogen Antibodies | PA1-843 | 13 references | Polyclonal |
WB
ICC
IHC
OA |
|
Proteintech Group | 20017-1-AP | 2 references | Polyclonal |
WB
EL
ICC
|
|
Novus Biologicals | NB120-5802 | Polyclonal |
WB
ICC
IP
IHC
ChIP
|
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NSJ Bioreagents | RQ8182 | Polyclonal |
WB
EL
ICC
FC |
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Enhanced validation
Supportive data in Antibodypedia
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Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider