Tissue expression
Cell line expression
Protein structure
EOMES
EomesoderminTBR2
This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Top validated antibodies |
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| Invitrogen Antibodies | 28 references | Monoclonal |
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| R&D Systems | 2 references | Monoclonal |
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| Novus Biologicals | 3 references | Monoclonal |
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| Biorbyt | Recombinant |
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| Cell Signaling Technology, Inc | Monoclonal |
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