UPF3A

gene product
HUPF3A, RENT3A, UPF3
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome 13. Several splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]
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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
1 antibody
Novus Biologicals
6 antibodies
Abnova Corporation
6 antibodies
LifeSpan BioSciences, Inc.
7 antibodies
NovoPro Bioscience Inc.
1 antibody
antibodies-online
28 antibodies
Acris Antibodies GmbH
1 antibody
Invitrogen Antibodies
2 antibodies
Atlas Antibodies
2 antibodies
Biorbyt
3 antibodies
Aviva Systems Biology
2 antibodies
OriGene
1 antibody
Creative Biolabs
3 antibodies
Creative Diagnostics
2 antibodies
RayBiotech, Inc.
1 antibody
MyBioSource
4 antibodies
Sigma-Aldrich
2 antibodies
Everest Biotech
1 antibody
GeneTex
1 antibody
St John's Laboratory
1 antibody
Abgent
1 antibody
ProSci
1 antibody