Tissue expression
Cell line expression
Protein structure
ARHGDIB
Rho GDP dissociation inhibitor betaGDIA2, GDID4, Ly-GDI, RAP1GN1, RhoGDI2
Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]). [supplied by OMIM, Dec 2010]
Top validated antibodies |
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Novus Biologicals | ![]() |
20 references | Monoclonal |
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Proteintech Group | ![]() |
6 references | Polyclonal |
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GeneTex | ![]() |
Monoclonal |
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antibodies-online | ![]() |
16 references | Monoclonal |
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LSBio | ![]() |
Polyclonal |
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