Tissue expression
Cell line expression
Protein structure
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase BBub1A, BUBR1, MAD3L, SSK1
This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Novus Biologicals | 1 references | Monoclonal |
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| Proteintech Group | 15 references | Polyclonal |
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| antibodies-online | 7 references | Monoclonal |
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| OriGene | Monoclonal |
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| LSBio | Monoclonal |
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