Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
SLC27A2
Solute carrier family 27 member 2ACSVL1, FACVL1, FATP2, hFACVL1, HsT17226, VLACS, VLCS
The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]
Top validated antibodies |
|||||
| Proteintech Group |  14048-1-AP |
9 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
|
| Invitrogen Antibodies | 14048-1-AP |
Polyclonal |
WB
ICC
IP
IHC
OA
|
||
| antibodies-online | ABIN1724864 |
2 references | Monoclonal |
WB
EL
IHC
|
|
| NovoPro Bioscience Inc. | 115362 |
Polyclonal |
WB
EL
ICC
IP
IHC
|
||
| Biorbyt | orb153480 |
Monoclonal |
WB
EL
ICC
IHC
FC
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive) Recommended by provider