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Protein structure
SLCO1B3
Solute carrier organic anion transporter family member 1B3OATP1B3, OATP8, SLC21A8
This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobiotic compounds and plays a critical role in bile acid and bilirubin transport. Mutations in this gene are a cause of Rotor type hyperbilirubinemia. Alternative splicing of this gene and the use of alternative promoters results in transcript variants encoding different isoforms that differ in their tissue specificity. [provided by RefSeq, Mar 2017]
Top validated antibodies |
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| Proteintech Group |  66381-1-Ig |
5 references | Monoclonal |
WB
EL
ICC
IHC
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| Novus Biologicals | NBP1-80980 |
2 references | Polyclonal |
WB
ICC
IHC
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| GeneTex | GTX15442 |
1 references | Monoclonal |
ICC
IP
IHC
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| St John's Laboratory | STJ72055 |
Polyclonal |
WB
EL
IHC
FC
OA
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| Atlas Antibodies | HPA004943 |
8 references | Polyclonal |
ICC
IHC
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