Tissue expression
Cell line expression
Protein structure
SRD5A3
Steroid 5 alpha-reductase 3FLJ13352, SRD5A2L, SRD5A2L1
The protein encoded by this gene belongs to the steroid 5-alpha reductase family, and polyprenol reductase subfamily. It is involved in the production of androgen 5-alpha-dihydrotestosterone (DHT) from testosterone, and maintenance of the androgen-androgen receptor activation pathway. This protein is also necessary for the conversion of polyprenol into dolichol, which is required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-linked glycosylation of proteins. Mutations in this gene are associated with congenital disorder of glycosylation type Iq. [provided by RefSeq, Mar 2011]
Top validated antibodies |
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Aviva Systems Biology | OAAB02693 | Polyclonal |
WB
EL
IHC
FC |
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NovoPro Bioscience Inc. | 123748 | Polyclonal |
WB
EL
IHC
FC |
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antibodies-online | ABIN2840258 | Polyclonal |
WB
IHC
FC
|
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Abgent | AP5276b | Polyclonal |
WB
IHC
FC
|
||
Invitrogen Antibodies | PA5-25200 | Polyclonal |
WB
IHC
FC
|
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Supportive data in Antibodypedia
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Supportive data in Antibodypedia
Data presented on provider website
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Recommended by provider