Tissue expression
Cell line expression
Protein structure

IL21R

Interleukin 21 receptor
CD360 
The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
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535 antibodies from 43 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
19 antibodies
Proteintech Group
2 antibodies
Novus Biologicals
23 antibodies
GeneTex
11 antibodies
NovoPro Bioscience Inc.
2 antibodies
antibodies-online
138 antibodies
Biorbyt
51 antibodies
Abnova Corporation
5 antibodies
R&D Systems
19 antibodies
OriGene
6 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
Enzo Life Sciences
1 antibody
Cusabio Biotech Co., Ltd
5 antibodies
ProSci
2 antibodies
Acris Antibodies GmbH
8 antibodies
Abgent
4 antibodies
BioLegend
21 antibodies
Atlas Antibodies
1 antibody
Boster Biological Technology
1 antibody
Abbkine Scientific Co.Ltd.
1 antibody
Bioworld Technology, Inc
1 antibody
Aviva Systems Biology
2 antibodies
St John's Laboratory
3 antibodies
DIMA
1 antibody
Miltenyi Biotec
8 antibodies
MyBioSource
15 antibodies
Leading Biology
5 antibodies
QED Bioscience
2 antibodies
Abbexa
7 antibodies
Creative Diagnostics
5 antibodies
GenWay
5 antibodies
Abbiotec
2 antibodies
EMD Millipore
1 antibody
Creative Biolabs
64 antibodies
MilliporeSigma / Merck KGaA
4 antibodies
RayBiotech, Inc.
2 antibodies
Absolute Antibody
5 antibodies
United States Biological
3 antibodies
Arigo
1 antibody
Rockland Immunochemicals, Inc.
2 antibodies
Kerafast Inc.
1 antibody