NME8

This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6. [provided by RefSeq, Nov 2009]

Description

NME/NM23 family member 8

Protein family

Disease related genes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

7:p14.1 (37848597 - 37900397)

Ensembl ID

ENSG00000086288  (ver. 99.38)

Orthologs

Mouse Nme8: ENSMUSG00000041138

UniProt

Q8N427

neXtProt

NX_Q8N427

Human splice variants
Mouse splice variants