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Protein structure
SMARCE1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1BAF57
The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| LSBio |  LS-C334010 |
Polyclonal |
WB
ICC
IP
IHC
ChIP
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| Atlas Antibodies | HPA003916 |
5 references | Polyclonal |
WB
ICC
IHC
ChIP
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| NSJ Bioreagents | RQ7665 |
Polyclonal |
WB
EL
ICC
IHC
FC
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| Proteintech Group | 10814-1-AP |
1 references | Polyclonal |
WB
EL
IP
IHC
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| Novus Biologicals | NB100-2591 |
4 references | Polyclonal |
WB
IP
IHC
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