TNFRSF25

gene product
APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
667 antibodies from 38 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
232 antibodies
LifeSpan BioSciences, Inc.
82 antibodies
Acris Antibodies GmbH
17 antibodies
Abnova Corporation
8 antibodies
Novus Biologicals
39 antibodies
R&D Systems
32 antibodies
NovoPro Bioscience Inc.
8 antibodies
OriGene
14 antibodies
GeneTex
5 antibodies
Invitrogen Antibodies
15 antibodies
Biorbyt
24 antibodies
Rockland Immunochemicals, Inc.
3 antibodies
Arigo
3 antibodies
Cell Signaling Technology, Inc
3 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Abgent
10 antibodies
ProSci
4 antibodies
Aviva Systems Biology
10 antibodies
Proteintech Group
1 antibody
BioLegend
4 antibodies
NSJ Bioreagents
2 antibodies
Atlas Antibodies
1 antibody
Miltenyi Biotec
10 antibodies
St John's Laboratory
3 antibodies
Creative Biolabs
40 antibodies
RayBiotech, Inc.
5 antibodies
Antibodies.com
2 antibodies
MyBioSource
12 antibodies
Creative Diagnostics
8 antibodies
Abbiotec
1 antibody
Boster Biological Technology
1 antibody
RabMAbs
1 antibody
United States Biological
29 antibodies
eBioscience, An Affymetrix Company
5 antibodies
Abbexa
2 antibodies
GenWay
2 antibodies
Sigma-Aldrich
4 antibodies