Tissue expression
Cell line expression
Protein structure
UBR5
Ubiquitin protein ligase E3 component n-recognin 5DD5, EDD, EDD1, HYD, KIAA0896
This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| antibodies-online | 7 references | Polyclonal |
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| Novus Biologicals | 7 references | Polyclonal |
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| LSBio | Polyclonal |
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| Proteintech Group | 4 references | Polyclonal |
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| Invitrogen Antibodies | Polyclonal |
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