PRKAG3

gene product
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle. [provided by RefSeq, Jul 2008]
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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
92 antibodies
Novus Biologicals
4 antibodies
LifeSpan BioSciences, Inc.
39 antibodies
Abnova Corporation
4 antibodies
Abgent
3 antibodies
Biorbyt
10 antibodies
Aviva Systems Biology
4 antibodies
OriGene
2 antibodies
GeneTex
2 antibodies
Acris Antibodies GmbH
2 antibodies
Invitrogen Antibodies
3 antibodies
St John's Laboratory
3 antibodies
NovoPro Bioscience Inc.
1 antibody
ProSci
3 antibodies
MyBioSource
3 antibodies
Cell Signaling Technology, Inc
1 antibody
United States Biological
39 antibodies
Creative Diagnostics
3 antibodies
Sigma-Aldrich
2 antibodies
Everest Biotech
1 antibody