FOXN3

This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms. [provided by RefSeq, Jul 2008]

Description

Forkhead box N3

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Plasma membrane

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
Transcription factors

Chromosome

14 (89124871 - 89619149)

Ensembl ID

ENSG00000053254  (ver. 103.38)

Orthologs

Mouse Foxn3: ENSMUSG00000033713

UniProt

O00409

neXtProt

NX_O00409

Human splice variants
Mouse splice variants

Protein structure