TNFRSF1B

gene product
CD120b, p75, TNF-R-II, TNF-R75, TNFBR, TNFR2, TNFR80
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
949 antibodies from 43 providers.

Antibody properties

General

Applications

or Cancel
Antibody
Proteintech Group
1 antibody
Novus Biologicals
69 antibodies
R&D Systems
40 antibodies
OriGene
37 antibodies
NovoPro Bioscience Inc.
16 antibodies
Invitrogen Antibodies
17 antibodies
GeneTex
16 antibodies
Boster Biological Technology
5 antibodies
antibodies-online
238 antibodies
Biorbyt
40 antibodies
Abnova Corporation
8 antibodies
Atlas Antibodies
1 antibody
LifeSpan BioSciences, Inc.
188 antibodies
Affinity Biosciences
5 antibodies
Acris Antibodies GmbH
37 antibodies
Aviva Systems Biology
5 antibodies
NSJ Bioreagents
5 antibodies
Bioworld Technology, Inc
2 antibodies
Enzo Life Sciences
2 antibodies
RabMAbs
2 antibodies
PeproTech Inc.
8 antibodies
Creative Biolabs
42 antibodies
St John's Laboratory
5 antibodies
Arigo
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Bioss
1 antibody
Cell Signaling Technology, Inc
1 antibody
Creative Diagnostics
11 antibodies
BioLegend
12 antibodies
MyBioSource
19 antibodies
ProSci
4 antibodies
BioLegend (formerly Covance Antibody Products)
1 antibody
Everest Biotech
1 antibody
Miltenyi Biotec
15 antibodies
GenWay
11 antibodies
United States Biological
66 antibodies
RayBiotech, Inc.
2 antibodies
Abiocode, Inc.
1 antibody
Leading Biology
2 antibodies
Abbiotec
1 antibody
Sigma-Aldrich
1 antibody
Sino Biological Inc.
6 antibodies
Abgent
2 antibodies