TRIM54

The protein encoded by this gene contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Description

tripartite motif containing 54

Protein family

Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

2:p23.3 (27282392 - 27307439)

Ensembl ID

ENSG00000138100  (ver. 99.38)

Orthologs

Mouse Trim54: ENSMUSG00000062077

UniProt

Q9BYV2

neXtProt

NX_Q9BYV2

Human splice variants
Mouse splice variants