PSAP

gene product
GLBA, SAP1
This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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318 antibodies from 30 providers.

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AntibodyRefsTypeAVIWBELICCIPIHCFC
Novus Biologicals
28 antibodies
GeneTex
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antibodies-online
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Acris Antibodies GmbH
6 antibodies
OriGene
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Atlas Antibodies
1 antibody
Abnova Corporation
13 antibodies
LifeSpan BioSciences, Inc.
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3 antibodies
Invitrogen Antibodies
3 antibodies
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Biorbyt
11 antibodies
Proteintech Group
5 antibodies
Bioworld Technology, Inc
1 antibody
Abgent
5 antibodies
St John's Laboratory
3 antibodies
Aviva Systems Biology
3 antibodies
R&D Systems
1 antibody
Signalway Antibody LLC
1 antibody
Creative Diagnostics
5 antibodies
ProSci
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
RabMAbs
2 antibodies
RayBiotech, Inc.
1 antibody
United States Biological
35 antibodies
MyBioSource
9 antibodies
Creative Biolabs
3 antibodies
Sigma-Aldrich
2 antibodies
Abbexa
3 antibodies