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Cell line expression
SLC6A1
gene productGABATHG, GABATR, GAT1
The protein encoded by this gene is a gamma-aminobutyric acid (GABA) transporter that localizes to the plasma membrane. The encoded protein removes GABA from the synaptic cleft, restoring it to presynaptic terminals. [provided by RefSeq, Jan 2017]
- Description
- Solute carrier family 6 member 1
- Tissue specificity
- Tissue enhanced (brain, liver, retina)
- Predicted location
- Membrane
- Protein family
- Disease related genes
FDA approved drug targets
Human disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted membrane proteins
Protein evidence (Kim et al 2014)
Transporters
- Chromosome
- 3:p25.3 (10992186 - 11039247)
- Ensembl ID
- ENSG00000157103 (ver. 103.38)
- Orthologs
- Mouse Slc6a1: ENSMUSG00000030310
- UniProt
- P30531
- neXtProt
- NX_P30531
Human splice variants
Mouse splice variants
| Ensembl | UniProt | RefSeq | Entrez |
|---|---|---|---|
|
ENSMUST00000032454 ENSMUSP00000032454 |
P31648.162 P31648 | NP_848818.1 NP_848818 | Slc6a1 232333 |
|
ENSMUST00000204074 ENSMUSP00000145080 |
Slc6a1 232333 |
* nTPM: Normalized TPM levels represent consensus gene expression calculated using two data sets. Read more
RNA data sourced from Human Protein Atlas.
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