AMFR

This locus encodes a glycosylated transmembrane receptor. Its ligand, autocrine motility factor, is a tumor motility-stimulating protein secreted by tumor cells. The encoded receptor is also a member of the E3 ubiquitin ligase family of proteins. It catalyzes ubiquitination and endoplasmic reticulum-associated degradation of specific proteins. [provided by RefSeq, Feb 2012]

Description

autocrine motility factor receptor

Protein family

Enzymes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Predicted membrane proteins, Protein evidence (Peptideatlas)

Chromosome

16:q13 (56361452 - 56425545)

Ensembl ID

ENSG00000159461  (ver. 99.38)

Orthologs

Mouse Amfr: ENSMUSG00000031751

UniProt

Q9UKV5

neXtProt

NX_Q9UKV5

Human splice variants
Mouse splice variants