ILKAP

The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway. [provided by RefSeq, Jul 2008]

Description

ILK associated serine/threonine phosphatase

Protein family

Enzymes, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014)

Chromosome

2:q37.3 (238170401 - 238203729)

Ensembl ID

ENSG00000132323  (ver. 84.38)

Orthologs

Mouse Ilkap: ENSMUSG00000026309

UniProt

Q9H0C8

neXtProt

NX_Q9H0C8

Human splice variants
Mouse splice variants