Tissue expression
Cell line expression
Protein structure
ESX1
ESX homeobox 1ESX1L, ESXR1
This gene encodes a dual-function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment with a paired-like homeodomain and a 20 kDa C-terminal fragment with a proline-rich domain. The C-terminal fragment localizes to the cytoplasm while the N-terminal fragment localizes exclusively to the nucleus. In contrast to human, the mouse homolog has a novel PN/PF motif in the C-terminus and is paternally imprinted in placental tissue. This gene likely plays a role in placental development and spermatogenesis. [provided by RefSeq, Jan 2010]
Top validated antibodies |
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antibodies-online | ![]() |
4 references | Polyclonal |
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Novus Biologicals | ![]() |
Polyclonal |
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Boster Biological Technology | ![]() |
Polyclonal |
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GeneTex | ![]() |
Polyclonal |
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Biorbyt | ![]() |
Polyclonal |
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