DMTF1

gene product
DMP1, DMTF, hDMP1, MRUL
This gene encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 40% of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
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246 antibodies from 25 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
5 antibodies
LifeSpan BioSciences, Inc.
46 antibodies
Abnova Corporation
3 antibodies
antibodies-online
85 antibodies
Abgent
4 antibodies
OriGene
7 antibodies
Aviva Systems Biology
6 antibodies
Atlas Antibodies
1 antibody
Invitrogen Antibodies
4 antibodies
Antibodies.com
2 antibodies
Boster Biological Technology
1 antibody
Biorbyt
10 antibodies
Acris Antibodies GmbH
2 antibodies
Everest Biotech
2 antibodies
NSJ Bioreagents
2 antibodies
ProSci
6 antibodies
Creative Biolabs
9 antibodies
Creative Diagnostics
5 antibodies
Arigo
1 antibody
GeneTex
1 antibody
United States Biological
21 antibodies
St John's Laboratory
2 antibodies
Sigma-Aldrich
4 antibodies
MyBioSource
5 antibodies