GALE

gene product
SDR1E1
This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
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250 antibodies from 27 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Biorbyt
10 antibodies
Abgent
1 antibody
Invitrogen Antibodies
5 antibodies
Novus Biologicals
6 antibodies
antibodies-online
97 antibodies
Aviva Systems Biology
3 antibodies
Atlas Antibodies
1 antibody
NovoPro Bioscience Inc.
1 antibody
LifeSpan BioSciences, Inc.
44 antibodies
ProSci
2 antibodies
Proteintech Group
1 antibody
GeneTex
2 antibodies
Boster Biological Technology
2 antibodies
NSJ Bioreagents
1 antibody
St John's Laboratory
1 antibody
OriGene
5 antibodies
Abnova Corporation
6 antibodies
Bioworld Technology, Inc
1 antibody
Abbexa
4 antibodies
RabMAbs
4 antibodies
Acris Antibodies GmbH
6 antibodies
MyBioSource
4 antibodies
Creative Biolabs
3 antibodies
United States Biological
24 antibodies
Creative Diagnostics
2 antibodies
Sigma-Aldrich
2 antibodies