SLC25A26

This gene is a member of the mitochondrial carrier family which includes nuclear-encoded transporters localized on the inner mitochondrial membranes. Members of the family transport important small molecules across the mitochondrial inner membrane. This protein is involved in the transport of S-adenosylmethionine (SAM) into the mitochondria. Mutations in this gene are associated with combined oxidative phosphorylation deficiency 28. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2017]

Description

Solute carrier family 25 member 26

Tissue specificity

Low tissue specificity

Subcell location

Mitochondria

Predicted location

Intracellular, Membrane

Protein family

Disease related genes
Human disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Potential drug targets
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
Transporters

Chromosome

3:p14.1 (66133610 - 66388116)

Ensembl ID

ENSG00000144741  (ver. 103.38)

Orthologs

Mouse Slc25a26: ENSMUSG00000045100

UniProt

Q70HW3

neXtProt

NX_Q70HW3

Human splice variants
Mouse splice variants