ASIC2
gene productACCN, ACCN1, ASIC2a, BNaC1, BNC1, hBNaC1, MDEG
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Feb 2012]
Featured antibodies
 Atlas Antibodies |
 HPA052112 |
0 references | Polyclonal |
WB
IHC
|
 Biorbyt |
orb39908 |
0 references | Polyclonal |
WB
EL 
IHC
FC
|
Antibodies
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Supportive data in Antibodypedia
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Validated within AVI
Eligible for validation within AVI