Tissue expression
Cell line expression
Protein structure
ASIC2
Acid sensing ion channel subunit 2ACCN, ACCN1, ASIC2a, BNaC1, BNC1, hBNaC1, MDEG
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Feb 2012]
Top validated antibodies |
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Invitrogen Antibodies | ![]() |
2 references | Polyclonal |
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Boster Biological Technology | ![]() |
1 references | Polyclonal |
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antibodies-online | ![]() |
1 references | Polyclonal |
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Proteintech Group | ![]() |
2 references | Polyclonal |
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NSJ Bioreagents | ![]() |
Polyclonal |
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