Tissue expression
Cell line expression
Protein structure
CCL11
C-C motif chemokine ligand 11eotaxin, MGC22554, SCYA11
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Sep 2014]
Top validated antibodies |
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R&D Systems | ![]() |
22 references | Polyclonal |
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Novus Biologicals | ![]() |
22 references | Polyclonal |
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Proteintech Group | ![]() |
2 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
4 references | Polyclonal |
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GeneTex | ![]() |
Polyclonal |
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