Tissue expression
Cell line expression

KRIT1

gene product
CAM, CCM1 
This gene encodes a protein containing four ankyrin repeats, a band 4.1/ezrin/radixin/moesin (FERM) domain, and multiple NPXY sequences. The encoded protein is localized in the nucleus and cytoplasm. It binds to integrin cytoplasmic domain-associated protein-1 alpha (ICAP1alpha), and plays a critical role in beta1-integrin-mediated cell proliferation. It associates with junction proteins and RAS-related protein 1A (Rap1A), which requires the encoded protein for maintaining the integrity of endothelial junctions. It is also a microtubule-associated protein and may play a role in microtubule targeting. Mutations in this gene result in cerebral cavernous malformations. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009]
More gene data

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207 antibodies from 27 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
65 antibodies
GeneTex
1 antibody
ReliaTech GmbH
2 antibodies
Cusabio Biotech Co., Ltd
4 antibodies
Acris Antibodies GmbH
3 antibodies
OriGene
2 antibodies
Novus Biologicals
5 antibodies
Biorbyt
11 antibodies
St John's Laboratory
1 antibody
Invitrogen Antibodies
5 antibodies
LifeSpan BioSciences, Inc.
28 antibodies
Abnova Corporation
4 antibodies
Creative Biolabs
7 antibodies
Atlas Antibodies
1 antibody
Aviva Systems Biology
1 antibody
NSJ Bioreagents
1 antibody
MyBioSource
4 antibodies
Abgent
1 antibody
Boster Biological Technology
1 antibody
NovoPro Bioscience Inc.
1 antibody
Creative Diagnostics
4 antibodies
MilliporeSigma / Merck KGaA
3 antibodies
Abbexa
1 antibody
United States Biological
33 antibodies
EMD Millipore
1 antibody
Leading Biology
1 antibody